Not to be administered concomitantly w/ other long-acting β-adrenergic agonists or long-acting muscarinic antagonists. Not for the treatment of asthma &/or acute episodes of bronchospasm. Discontinue immediately if hypersensitivity &/or paradoxical bronchospasm occurs. Narrow-angle glaucoma or urinary retention; CV disorders (eg, CAD, acute MI, cardiac arrhythmias, HTN); convulsive disorders or thyrotoxicosis, patients unusually responsive to β2-adrenergic agonists. Not to be used more often or at higher doses than recommended. Discontinue upon increase in pulse rate, BP &/or symptoms of CV effects. Hypokalemia may be potentiated by hypoxia & concomitant treatment which may increase susceptibility to cardiac arrhythmias in patients w/ severe COPD. May increase plasma glucose w/ high dose. Closely monitor plasma glucose in diabetic patients upon initiation. Patients w/ rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Severe renal impairment or ESRD requiring dialysis. Pregnancy & lactation. May inhibit labor due to relaxant effect on uterine smooth muscle. Not to be used in childn <18 yr.
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